Proteins work to keep the fluid and Acid-Base Balance in the body

Water moves toward areas with higher concentrations of some solutes, such as glucose and proteins. To keep the water evenly distributed between blood and cells, proteins continuously circulate at relatively high concentrations in the blood.

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The protein of abundance in the blood is the protein known as albumin. Albumin is a simple water-soluble protein, and its existence and presence in the blood make the protein concentration in the blood equal to that in cells. Thus, the fluid exchange between cells and the blood is balanced to preserve a dynamic state of equilibrium. Albumin functions as a buffer against abrupt changes in the concentrations of other molecules, thereby balancing blood acid-base balance and maintaining the steady state of equilibrium. The hemoglobin protein in the blood also keeps the acid-base balance by binding and releasing protons.